The Team of Doctors and Biohackers Who Seem to Be Successfully Treating “Long Covid”

While trying to understand the mechanism of Long Covid, which obviously involved serotonin dysfunction balanced by mast cell activation as I wrote about previously - I met a group who seems to have the last pieces of the puzzle and the ultimate scientific validation: they appear to be giving people their lives back using low cost compounds anyone can buy at the pharmacy, the ultimate application and validation of a scientific theory.

Their research, COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity, has received an excellent response and seems to be validated in mice, relevant abnormalities found in ferrets and the mechanism echoed by other researchers. Dysfunction of relevant systems are found in COVID19 and correlated with inflammatory markers. Clinical trials are under way to treat the same mechanism using more exotic and commercial compounds than the simple ones used with success in their case.

According to this theory, cofactors coupled to the oxidation/NAD+ cascade are critical to outcomes and this is seen in the observation that low selenium levels correlated to poor outcomes in China. Observations of high blood sugar being a predictor of death in COVID19 patients, regardless of diebetic status…